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Whiskey · Modern Classic · Spicy

Penicillin Recipe

Smoky, honeyed, ginger-hot — the most-copied new cocktail of the last twenty years.

Prep Time
1.5 min
Method
Shaken
Glass
Rocks glass
Strength
Balanced

Every recipe on Sipped Right is tested for taste and balance before it's published.

Last updated September 14, 2026

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About the Penicillin

Created by bartender Sam Ross at Milk & Honey in New York around 2005. Unlike most cocktail origins, this one is well-documented and not seriously disputed.

Penicillin cocktail served in a Rocks glass
Ingredients for a Penicillin: Blended Scotch, Fresh lemon juice, Honey-ginger syrup laid out on a home kitchen counter

Ingredients

Servings
1
  • Blended Scotch2 oz
  • Fresh lemon juice¾ oz
  • Honey-ginger syrup¾ oz
  • Peaty Islay Scotch¼ oz , for float

Method

  1. Measure and pour the blended Scotch, fresh lemon juice and honey-ginger syrup into the shaker.
  2. Add a scoop of ice to the shaker.
  3. Shake for 15 seconds.
  4. Strain the cocktail over a large cube.
  5. Float the peaty Islay Scotch over the back of a spoon.
Shaking the Penicillin into a chilled rocks glass
Close-up of the garnish on a Penicillin, expressed over the glass

Glass & Garnish

Rocks glass, over one large cube.

Notes

Make honey-ginger syrup with equal parts honey/water and fresh ginger, strained. No float Scotch? The drink still works, minus the smoke on the nose. Pairs well with aged cheese.

Tools Used

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